ABSTRACT
【Objective】In-vitro antibacterial activity of the combination of Herba Violae(HV)and Herba Taraxaci(HT)in different proportions was compared and analyzed for the optimization of the combination proportion of Herba Violae and Herba Taraxaci and the influencing factors.【Methods】The minimum inhibitory concentration(MIC)of the combination of HV and HT was determined by agar double dilution method and the minimum bactericidal concentration(MBC)by broth dilution method,and bactericidal curve was traced.Meanwhile,the resistance of the combination of HV and HT induced by sub-inhibitory concentration was analyzed,and the influencing factors of in-vitro antibacterial activity were investigated.【Results】The combination of HV and HT in the proportion of 1∶4 had a better antibacterial activity on four kinds of gram-positive bacteria and on four kinds of gramnegative bacteria,and exerted an bactericidal effect on Escherichia coli and Klebsiella Pneumoniae(both MBC_(50)/MIC_(50) and MBC_(90)/MIC_(90) being 2).The bactericidal curve showed that 2?Log cfu/mL bacteria strain could be killed by the combination of the proportion being 1∶4 at 8~(th) hour,the effect being superior to that of other two combinations.Inoculation dosage,serum amount and pH value had no effect on in-vitro antibacterial activity.【Conclusion】The combination of HV and HT in the proportion of 1∶4 has a better antibacterial activity.
ABSTRACT
AIM: To investigate the influence of aspirin on the efficacy of captopril in the treatment of chronic congestive heart failure (CHF). METHODS: 74 cases of CHF were divided into 2 groups depending on whether aspirin was administrated before captopril was given, then all patients were given captopril 12.5 - 25 mg , tid, for 28 days. RESULTS: In aspirin group, marked effective rate was 46.7 %, and total effective rate was 70%, superior to that in no aspirin group (P
ABSTRACT
Objective To observe the effect of the method of clearing the upper for treating the lower for treatment of chronic glomerulonephritis (CGN) complicated with tonsillitis and pharyngitis. Methods The changes of indices of 120 patients after treatment of herbal decoction were observed and analyzed. Results The Complete remission was 25 cases (20.8%), fundamental remission 42 cases (35%), improvement 38 cases (31.7%), and inefficacy 15 cases (12.5%). The total effective rate was 87.5%. The shorter the course of disease, the milder the pathological condition, the better the effect. The indices of qualitative examination of urinary protein and urinary RBC and WBC were significantly improved (P0.05). SCr and BUN of those patients with abnormal renal functions were all improved significantly after herbal treatment (P